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Zoloft Side Effects

Zoloft's main active ingredient is Sertraline, and it was launched in 1992 for the treatment of major depressive disorder. It is also approved for the treatment of panic disorder, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

Common Zoloft Side Effects

Dizziness, dry mouth, fatigue, tingling or pins and needles, gas, headache, abdominal pain, agitation, anxiety, constipation, decreased sex drive, diarrhea or loose stools, difficulty with ejaculation, decreased appetite, increased sweating, indigestion, insomnia, nausea, nervousness, pain, rash, sleepiness, sore throat, tremor, vision problems, vomiting.

It is quite possible for side effects other than those listed here to occur. If this happens and/or if any seem particularly strange or bothersome, contact a healthcare provider.

Special Zoloft Precautions

Individuals should not take Zoloft within two weeks of taking any drug classified as an MAO inhibitor. Drugs in this category include the antidepressants Marplan, Nardil, and Parnate. When serotonin boosters such as Zoloft are combined with MAO inhibitors, serious and sometimes fatal reactions may occur.

In a few people, Zoloft may trigger the grandiose, inappropriate, out-of-control behavior called mania or the similar, but less dramatic, "hyper" state called hypomania.

Patients with a kidney or liver disorder, or who are subject to seizures, should take Zoloft cautiously and under close medical supervision. A doctor may actually limit the dosage if patient has one of these conditions.

Alcoholic beverages should not be consumed while taking Zoloft and use of over-the-counter remedies at the same time must be done with caution. Although unconfirmed, interactions remain a possibility thus exercise caution.

If Zoloft is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zoloft with the following drugs - Cimetidine (Tagamet), Diazepam (Valium), Digitoxin (Crystodigin), Flecainide (Tambocor), Lithium (Eskalith, Lithobid), MAO inhibitor drugs such as the antidepressants Nardil and Parnate, Other serotonin-boosting drugs such as Paxil and Prozac, other antidepressants such as Elavil and Serzone , over-the-counter drugs such as cold remedies, Propafenone (Rythmol), Sumatriptan (Imitrex), Tolbutamide (Orinase) and Warfarin (Coumadin).

Patients who are using the oral concentrate form of Zoloft, should not take disulfiram (Antabuse).

Warning: This information is intended to supplement, not be a substitute for the expertise and judgment of a doctor. Please consult a doctor for final and more detailed information about the possible side effects of this prescription medication.
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